Do GLP-1 Medications Cause Muscle Loss?

Woman maintaining muscle strength during GLP-1 weight loss

Weight loss during GLP-1-based treatment can include reductions in both fat mass and lean mass. Research involving semaglutide and tirzepatide shows that fat generally accounts for the larger share of weight lost, but lean tissue can also decrease. That does not mean every decrease in lean mass represents medication-caused muscle loss. Lean mass is broader […]